The CD51/61 antibody (FITC) from MyBioSource.com is a Mouse Monoclonal antibody. The CD51/61 antibody (FITC) has been validated for the following applications: Flow Cytometry.
Description
Mouse monoclonal CD51/61 antibody (FITC)
The 23C6 monoclonal antibody reacts with the human CD51/CD61 dimer, also known as the integrin alphav/beta3. CD51, an ~120 kDa surface molecule can also non-covalently associate with other beta subunits of the integrin family including beta1, beta5 and beta6 to form receptors for extracellular matrix components. Heterodimers of CD51/CD61 are expressed by melanoma cells, endothelial cells and osteoclasts and at very low levels by platelets. The CD51/CD61 complex mediates adhesion to fibrinogen, fibronectin, vitronectin and thrombospondin